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Clinical Trials are Recruiting!
current as of August 9, 2026, check clinicaltrials.gov to confirm
Alzheimer's Disease Trials
Remternetug
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Sponsor: DIAN-TU / Washington University-linked autosomal dominant Alzheimer's network
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Trial ID: NCT06647498
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Who it is for: Asymptomatic people at risk because of Alzheimer's disease-causing mutations
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Link: https://clinicaltrials.gov/study/NCT06647498
Trontinemab
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Sponsor: Roche / Genentech
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Trial ID: NCT07169578
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Who it is for: Early symptomatic Alzheimer's disease, from mild cognitive impairment to mild dementia
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Link: https://clinicaltrials.gov/study/NCT07169578
CpG 1018 ISS
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Sponsor: NYU Alzheimer's Disease Research Center
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Trial ID: No NCT listed in the initial search
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Who it is for: Mild cognitive impairment or mild Alzheimer's dementia; immune-stimulation approach
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Links: https://med.nyu.edu/centers-programs/alzheimers-disease-research/research/clinical-trials,
https://clinicaltrials.gov/study/NCT06976216
VHB937
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Sponsor: Novartis Pharmaceuticals
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Trial ID: NCT07094516
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Who is it for: People with early Alzheimer's disease
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Link: https://clinicaltrials.gov/study/NCT07094516
Parkinson's Disease Trials
GT-02287
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Sponsor: Gain Therapeutics
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Trial ID: NCT07280299
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Who is it for: Patients with early Parkinson's disease
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Links: learn more, https://clinicaltrials.gov/study/NCT07280299
AAV2-GDNF
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Sponsor: AskBio
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Trial ID: NCT06285643
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Who is it for: Adults with moderate Parkinson's disease
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Link: https://clinicaltrials.gov/study/NCT06285643
Prasinezumab
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Sponsor: Roche / Genentech and Prothena
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Trial ID: NCT07174310
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Who it is for: Early-stage Parkinson's disease
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Link: https://clinicaltrials.gov/study/NCT07174310
Bemdaneprocel
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Sponsor: BlueRock Therapeutics / Bayer
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Trial ID: NCT06944522
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Who it is for: Parkinson's disease; dopaminergic cell therapy compared with sham surgery
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Link: https://clinicaltrials.gov/study/NCT06944522
Buntanetap
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Sponsor: Annovis Bio
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Trial ID: NCT07284784
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Who it is for: Parkinson's disease
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Link: https://clinicaltrials.gov/study/NCT07284784
Prasinezumab
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Sponsor: Roche / Genentech
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Trial ID: NCT07055087
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Who it is for: Parkinson's disease with GBA-related cognitive-risk focus
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Verify: https://clinicaltrials.gov/study/NCT07055087
ALS / FTD Trials
Pridopidine
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Sponsor: Prilenia
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Trial ID: NCT07322003
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Who it is for: Adults with ALS
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Link: https://clinicaltrials.gov/study/NCT07322003
COYA-302
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Sponsor: Coya Therapeutics
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Trial ID: NCT07161999
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Who is it for: Adults with ALS
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Link: https://clinicaltrials.gov/study/NCT07161999
VTx-002
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Sponsor: Vector Y Therapeutics
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Trial ID: NCT07287397
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Who is it for: Adults with ALS
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Link: https://clinicaltrials.gov/study/NCT07287397
AMX0114
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Sponsor: Amylyx Pharmaceuticals
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Trial ID: NCT06665165
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Who is it for: Adults with ALS
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Link: https://clinicaltrials.gov/study/NCT06665165
Tofersen in non-SOD1 ALS
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Sponsor: Washington University School of Medicine
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Trial ID: NCT07294144
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Who is it for: Adults with ALS not caused by mutations in SOD1
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Link: https://clinicaltrials.gov/study/NCT07294144
AVB-101, ASPIRE-FTD
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Sponsor: AviadoBio
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Trial ID: NCT06064890
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Phase/status: Phase 1/2; recruiting
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Who it is for: FTD-GRN gene therapy; U.S. site at Ohio State reported
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Link: https://clinicaltrials.gov/study/NCT06064890
Multiple Sclerosis Trials
Frexalimab
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Sponsor: Sanofi
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Trial ID: NCT07325292
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Who it is for: Relapsing MS and non-relapsing SPMS; subcutaneous vs IV administration
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Link: https://www.sanofi.com/en/clinical-trials/nct07325292
Orelabrutinib
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Sponsor: InnoCare
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Trial ID: NCT07067463
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Who it is for: Primary progressive or progressive multiple sclerosis, depending on site
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Link: https://clinicaltrials.gov/study/NCT07067463
Huntington's Disease Trials
Pridopidine
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Sponsor: Prilenia
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Trial ID: NCT07609108
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Who is it for: Adults with Huntington's Disease
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Link: https://clinicaltrials.gov/study/NCT07609108
hNSC-01
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Sponsor: Leslie Thompson, University of California Irvine
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Trial ID: NCT07451613
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Who is it for: Adults with Huntington's Disease
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Link: https://clinicaltrials.gov/study/NCT07451613
Votoplam
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Sponsor: Novartis
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Trial ID: NCT07326709
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Who it is for: Early symptomatic Huntington's disease
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Links: https://www.novartis.com/clinicaltrials/study/nct07326709, https://clinicaltrials.gov/study/NCT07326709
SKY-0515
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Sponsor: Skyhawk Therapeutics
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Trial ID: NCT07378644
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Who it is for: Huntington's disease
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Link: https://clinicaltrials.gov/study/NCT07378644
Stroke and Ischemic Brain Injury Trials
ASP2246
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Sponsor: Astellas
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Trial ID: NCT07318714
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Who it is for: Chronic post-stroke motor impairment
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Link: https://clinicaltrials.gov/study/NCT07318714
NEUROVINC
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Sponsor: National University Hospital, Singapore
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Trial ID: NCT05679739
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Who it is for: Acute ischemic stroke / cerebral blood-flow strategy
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Link: https://clinicaltrials.gov/study/NCT05679739
Inhaled nitric oxide during thrombectomy
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Sponsor: Wake Forest University
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Trial ID: NCT05871606
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Who it is for: Acute ischemic stroke undergoing clot retrieval
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Links: https://www.withpower.com/trial/phase-1-ischemic-stroke-5-2023-7e3c0, https://clinicaltrials.gov/study/NCT05871606
Traumatic Brain Injury Trials
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Sponsor: Northwestern University
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Trial ID: NCT07166393
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Who it is for: Moderate-to-severe TBI
CIPN Trials
SIR2501
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Sponsor: Sironax
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Trial ID: NCT07765446
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Phase/status: Phase 1b/2 ongoing per company
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Who it is for: CIPN and ALS development program
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Link: https://www.sironax.com/sironaxs-sarm1-inhibitor-sir2501-granted-fda-fast-track-designation-in-chemotherapy-induced-peripheral-neuropathy-cipn-2/
Psilocybin
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Sponsor: M.D. Anderson Cancer Center
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Trial ID: NCT07227909
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Who it is for: Prevention or mitigation of CIPN during chemotherapy
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Link: https://clinicaltrials.gov/study/NCT07227909
Spinal cord stimulation
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Sponsor: Assistance Publique Hopitaux De Marseille
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Trial ID: NCT07579611
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Who it is for: Painful CIPN
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Link: https://clinicaltrials.gov/study/NCT07579611
Spinal cord stimulation for CIPN
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Sponsor: Mayo Clinic
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Trial ID: NCT05411523
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Who it is for: Painful CIPN / cancer-related neuropathic pain
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Link: https://www.mayo.edu/research/clinical-trials/cls-20530343
CMT and Peripheral Neuropathy Trials
CMT natural history and genetics
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Sponsor: Inherited Neuropathies Consortium
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Trial ID: NCT01193075 / NCT01193088
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Who it is for: CMT natural history, genetic modifiers, and trial readiness
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Link: https://clinicaltrials.gov/study/NCT01193088
Friedreich's Ataxia Trials
Omaveloxolone
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Sponsor: Biogen / Reata
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Trial ID: NCT06953583
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Who it is for: Pediatric Friedreich's ataxia
Nomlabofusp
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Sponsor: Larimar Therapeutics
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Trial ID: NCT06447025
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Who it is for: Friedreich's ataxia
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